The research paper delves into the enduring Israel-Palestine conflict and its profound impact on Palestinian human rights. Originating in the establishment of Israel in 1948, the conflict persists with ongoing violence and destruction. Despite international interventions, issues like forced displacement and settlement construction continue, and proposed solutions remain unimplemented. The research focuses on the period from 2000 to 2020, aiming to understand the extensive human rights violations endured by Palestinians, supported by evidence of thousands of casualties and restrictive measures. The methodology involves historical research, utilizing UN databases and NIH archives for quantitative and qualitative data. Coding will help analyze key themes, providing a nuanced perspective on the multifaceted human rights challenges faced by Palestinians in the conflict.