Plastic pollution is found everywhere in the environment due to its incapability to decompose. Plastic also poses health risks with microplastics entering the food chain and potentially causing issues like fertility problems and inflammation. The motivation behind this study arises from the shortcomings of current plastic waste management methods, such as recycling and incineration, and their adverse environmental impacts. To address this, I will conduct a comprehensive literature review of studies over the past five years to assess the feasibility, success, and challenges of various methods and advances in biological approaches to plastic degradation. Utilizing qualitative and quantitative methods, I plan to analyze the efficiency, capability, and cost of different biological methods. The significance of this research lies in its potential to provide innovative solutions to plastic pollution, contributing valuable insights that can inform policymakers, researchers, and the public. Ultimately, the goal is to publish this research in scientific journals or news sources, sharing crucial information that could lead to a safer and more sustainable way of managing plastic waste.