What novel stem cell and prostate cancer biomarkers located on the cell surface can researchers and clinicians use as therapeutic targets?

This study focuses on discovering novel stem cell and prostate cancer biomarkers located on the cell surface that researchers and clinicians can use as therapeutic targets. To achieve this, gene expression data from mouse microarray and human RNA-Seq sources were analyzed. Results from the data analysis were sorted to identify upregulated genes that may be associated with prostate cancer.

How does inserting different transitional metal atoms into a 6 by 6 cell of silicene affect its catalytic properties?

Monolayer 2D materials such as graphene, silicene, and boron-nitride are known to have interesting electronic properties. Currently, researchers are intrigued with the possibility of combining these 2D materials with transition metals to form new functionalized materials. The present studies have dealt with the incorporation of these metals on the surface to increase the functionality of 2D materials.

Is there a correlation between the rate at which a pulsar loses rotational energy and the non-thermal radiation and bulk kinetic energy of expansion of its supernova remnant?

Pulsars have been at the center of astronomical research since their discovery in 1967. This project examines the correlation between the rate at which a pulsar loses rotational energy and the non-thermal radiation and bulk kinetic energy of expansion of its supernova remnant. It has been shown, using the Crab pulsar-nebula system, that the rate of decrease of energy has a strong correlation to the energy in the surrounding nebula. This study will analyze the applicability of this relationship to other pulsar-nebula systems.  

How does the protein Ptch in the Hh pathway bond with cholesterol?

This project studies a segment of the Hedgehog pathway, a signaling pathway in vertebrates that regulates tissue patterning and development, and has been found to be closely linked with many varieties of cancer. Ptch is an important receptor protein within Hedgehog that activates the pathway in cells. By creating mutagenic Ptch (mutated versions of the protein) and running them through various assays, the goal is to ascertain what role cholesterol binding to Ptch has in the Hedgehog pathway, and which sequences in Ptch are important for successful cholesterol binding.

How does the amount of sleep affect an adolescent athlete's performance?

This project is focused on exploring the effects of sleep deprivation on emotional states and athletic performance of student athletes (basketball and swimming) ranging from the ages of 14 to 18 from both Palo Alto High Schools. The amount of sleep the subjects obtain for two weeks along with their free throw percentages/ lap times, or POMS test results will be recorded.The goal is to discover how the amount of sleep a teenager, or specifically, a student athlete obtains, affects their athletic performance and emotional state.

How can user mouse movement patterns be used to improve A/B testing?

This project will be studying mouse patterns such as mouse coordinates, and their use of left and right clicks on social media sites such as Facebook and Reddit. This study will target the demographic of high school students and websites they commonly use, which will direct this study in a more specific way. Data will be collected through a chrome extension and then loaded onto a Java program, which can calculate statistics and display the data. Patterns will be observed both visually and mathematically.

How can machine learning be used to analyze a website’s design by using data about human preferences based on age and/or gender? How can it provide insight on the website entrance's appeal to its target audiences?

This research project has two main components. The first component is a research study that collects data on people's website design preferences. The second component is constructing a machine learning program that uses that data to analyze and review a website. The main goal of this project is to create a product that people can use to see what is wrong with their websites, so that they can make their websites better for the future.

What kind of peptide chain inhibitor can be created to suppress the FOXP3 transcription factor and impair the development of regulatory T cells?

FOXP3, a protein that takes part in the development of regulatory T cells, is vital for the immune system in recognizing foreign from self cells. However, cancer as well as some autoimmune diseases take advantage of this to hide carcinogenic cells. Consequently, the aim of this research project is to work towards developing improvements for existing inhibitors for FOXP3.

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