Molecular Mechanisms Underlying Neurodegenerative Diseases Associated with Mutant Tau

Alzheimer's disease is the 6th leading cause of death in the United States, but currently, there is no cure (Alzheimer’s Association). To treat Alzheimer's disease, we must first fully understand the molecular mechanisms behind it and the pathological roles of the tau protein that classify diseases such as Alzheimer's disease as tauopathies. The tau protein has the normal role of attaching to and organizing microtubules, which are crucial for maintaining cell structure, transporting materials within cells, and separating chromosomes during cell division. Among other causes, mutations in the tau gene have been linked with pathological tau and the degeneration of neurons. I intend to research the effects of such mutations in a particular region of the gene, known as exon 10, on tau function and cell viability with both database and lab observational techniques.

Analyzing Different Prime Factorization Algorithms

In this project, I am researching and analyzing different prime factorization algorithms. After making a list of different algorithms, I will figure out the time complexity. Then, I will code the algorithm and retrieve real running time on variously sized input data sets. After collecting my data, I will compare each algorithm and extrapolate the existence of "fast" factorization algorithm.

Using a Neural Network to Predict Social Media Reactions to the Aesthetic Qualities of an Image

The goal of this project is to build a computational model to predict how many “likes” images will get from users of social media. The model will be trained and tested for accuracy by using data sourced from social networks. This data may be collected automatically with a computer program. This work is intended to help content creators improve their products.

Self-Folding Robots: How They Work and What Applications They Have

I am researching what self-folding robots are being used for and how they work. I am also making my own model of a self-folding robot using cheap and easily accessible materials that can be found in many local and online stores. My goal is to understand the mechanics of these robots and ultimately how they will be applied in science and everyday life.

RNA Folding with CoFold

My project involves simulating RNA cotranscriptional folding to find certain conditions that allow folding into specific shapes. These shapes can be used to create nanoscale devices such as motors or logic gates. They have implications in the industrial and medical fields, such as for manufacturing or drug delivery.

How Stealth Aircraft Can Reduce the Cross-Section of Sensor Fusion

I am building my own sensor fusion comprised of ultrasonic, sonar, and infrared sensors. Afterward, I will build my own stealth aircraft from scratch and tweak the structure to test methods for helping the aircraft evade detection by the sensor fusion. Aerodynamics, engine emission, and skin coating will be the three main factors I will be testing.

Basics of Acoustics

This research introduces the relationship and the ratio between sound frequency and pitch. By providing information and conclusion from articles written by experts in the field, this research also investigates why the ratio between sound frequency and pitch is inconsistent, as well as the psychological influences that affect how human beings hear certain high-frequency sound.

The Effect of Culturally Responsive Therapists for Minority Students

The focus of this project is to identify if minority students in Palo Alto High School would feel better supported in their mental health seeking services if they were treated by a professional who is trained to be culturally responsive or who shares a culture or identity with the student. The aim of this project is to see if this relationship will make more minority students comfortable with utilizing or continuing to undergo important therapy and counseling services.

Relationships between Sleep Patterns in Introversion/Extroversion

I will conduct a survey using verified tools to determine whether a person expresses morningness or eveningness. In simple terms, one who expresses morningness tends to work better in the morning, and one who expresses eveningness tends to work better in the evening. I will use this in conjunction with another tool to determine whether a person is an introvert or extrovert. These two sets of data will help me find correlations between M/E and introversion/extroversion.

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